Restylane and Perlane
Restylane is a safe and natural cosmetic dermal filler that restores volume and fullness to the skin to correct facial wrinkles and folds, such as nasolabial folds.
Restylane has a highly favorable safety profile. It is composed of non-animal stabilized hyaluronic acid. Hyaluronic acid is a substance found naturally in the human body. Restylane is fully biocompatible. There is limited risk of animal-based disease transmission or development of allergic reactions to animal proteins. No allergy testing is required before use.
Restylane maintains its shape using the body’s own moisture. The hyaluronic acid in Restylane is hydrophilic or “water loving.” As hyaluronic acid gradually degrades, each molecule binds to more water and over time, the same volume can be maintained with less hyaluronic acid. This ability of hyaluronic acid to bind to water is what helps provide long-lasting results.
Unlike rooster-derived hyaluronic acids and bovine collagen products, Restylane is free from animal proteins. This limits any risk of animal-based disease transmissions or development of allergic reactions to animal proteins.
Perlane®
Perlane restores volume and fullness to the skin to correct moderate to severe facial wrinkles and folds, such as the lines from your nose to the corners of your mouth (nasolabial folds). After your treatment, you might have some swelling, redness, pain, and bruising. This will normally last less than seven days. Although rare, red or swollen small bumps may occur. If you have had herpes before, an injection can cause the herpes to return. In rare circumstances, the doctor may inject into a blood vessel, which can damage the skin. To avoid bruising and bleeding, you should not use Perlane if you have recently used drugs that thin your blood or prevent clotting. If you are pregnant, breastfeeding, or under 18, you shouldn’t use Perlane.
For information on Perlane® and the Restylane Rewards® program, please contact the Restylane Rewards Customer Service Center toll-free at 800 211-6794, 9 AM to 5 PM Eastern time. More information on Perlane and the Restylane Rewards program is available at http://www.restylaneusa.com/rewards.asp.


Chelsea Medicine and Laser Center in Chelsea Michigan, just west of Ann Arbor, specializes in laser and non-surgical aesthetic medicine and skin care for patients of all ages, male and female. Let us help you attain and maintain a healthy, youthful appearance! Please call the office at 734-475-2921 to book an appointment for the most up to date medical and aesthetic care with the personal touch and efficiency of a small office.
